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 Scientists have begun to unlock the genetic code to understand how the lining of the bladder functions as a barrier to store urine -- paving the way for possible new treatments for chronic bladder diseases such as interstitial cystitis and cancer.

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joseph_abney34



Posts : 23
Join date : 2016-01-31

PostSubject: Scientists have begun to unlock the genetic code to understand how the lining of the bladder functions as a barrier to store urine -- paving the way for possible new treatments for chronic bladder diseases such as interstitial cystitis and cancer.   Sun Jul 16, 2017 4:47 pm

I don't know how this 3 month old article in science daily passed me by but here it is. https://www.sciencedaily.com/releases/2017/03/170314111313.htm
Summary: Researchers at the University of York used bioinformatics to look more closely at proteins called transcription factors (TFs)1 which bind along the DNA and control whether genes are switched on or off. Using a bioinformatics approach to map TF binding to the DNA, the Earlham Institute revealed that the TFs are actually arranged in a more complex or non-hierarchical pattern, where some may even compete for binding to the same DNA regions at different stages of the cell specialisation process. Basically they say if the can figure out which transcription factors bind where and when, then this information would provide the key to manipulating stem or precursor cells to form fully functional tissues for use in restorative medicine.

Interesting stuff, I'm sure the professor probably heard about this at his trip to the urology conference last month, but I wanted to post this to make sure the team was aware of this. Anyway, have a good one everybody and good luck with the research!
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Tina2



Posts : 149
Join date : 2016-02-15
Location : Queensland Australia

PostSubject: Re: Scientists have begun to unlock the genetic code to understand how the lining of the bladder functions as a barrier to store urine -- paving the way for possible new treatments for chronic bladder diseases such as interstitial cystitis and cancer.   Sun Jul 16, 2017 5:14 pm

The most important thing is that at long last researchers and the medical proffesion are looking for a cause and hopefully they will then come up with a cure rather than more medication that has awful side effects
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Scientists have begun to unlock the genetic code to understand how the lining of the bladder functions as a barrier to store urine -- paving the way for possible new treatments for chronic bladder diseases such as interstitial cystitis and cancer.
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