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 New IC Bladder Lining research breakthrough 03/14/2017 University of York

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joseph_abney34



Posts : 21
Join date : 2016-01-31

PostSubject: New IC Bladder Lining research breakthrough 03/14/2017 University of York   Thu Mar 16, 2017 2:06 am

At the University of York they posted a study yesterday that claims "Scientists have begun to unlock the genetic code to understand how the lining of the bladder functions as a barrier to store urine - paving the way for possible new treatments for chronic bladder diseases such as interstitial cystitis and cancer" In the article they discuss "Which genes are active in a particular tissue is partly decided by proteins called transcription factors (TFs)1 which bind along the DNA and control whether genes are switched on or off." At the end of the article he summarizes his conclusion 'Dr Fishwick said: "A key finding was that binding sites for different transcription factors were often co-located along the genome. This means that transcription factors could either compete or co-operate for binding to the same DNA regions. This can explain how cells mature within a tissue as transcription factors change. Our experiments also show that if a particular transcription factor is over-represented or absent, this can change the balance of gene expression in a cell and lead to disease." ' I wanted to post the link to this article so hopefully the doctors could see it and incorporate their new findings with their own research. Here is the link to the article on science daily  that was posted yesterday by the University of York https://www.sciencedaily.com/releases/2017/03/170314111313.htm  

And here is the DOI link to the original study in the Journal Nature Cell Death and Differentiation http://www.nature.com/cdd/journal/vaop/ncurrent/full/cdd201710a.html
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Tina2



Posts : 149
Join date : 2016-02-15
Location : Queensland Australia

PostSubject: Re: New IC Bladder Lining research breakthrough 03/14/2017 University of York   Thu Mar 16, 2017 6:07 am

Thank you Joseph ! very interesting, maybe we are starting to see some hope finally. If nothing else at least people all over the world are finally taking Bladder disease seriously and searching for a cure.
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lak78



Posts : 24
Join date : 2016-01-05
Location : Brisbane, Australia

PostSubject: Re: New IC Bladder Lining research breakthrough 03/14/2017 University of York   Sat Mar 18, 2017 6:54 am

Thanks for keeping us updated Joseph. It's so great to see progress is being made and these posts are what keep us ICers going Smile
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